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Conversion of cholesterol to bile acids is
2019-06-13
Conversion of cholesterol to bile acids is the only significant catabolic pathway for elimination of excessive cholesterol in our body. Bile acids have long been recognized as important physiological agents that facilitate ppar antagonist of dietary fats, steroids, drugs, and lipid soluble vitamins
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The comparative consensus modelling approach used by
2019-06-13
The comparative consensus modelling approach used by Eaton and colleagues is now used frequently to justify the implementation of particular HIV interventions. However, this approach produces meaningful results only if the comparison is based on valid models. Most comparative consensus studies (incl
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Randomised controlled trials of educational interventions ha
2019-06-13
Randomised controlled trials of educational interventions have also reported evidence to support the view that increased education is likely to be protective against infection. However, most education-focused trials are not designed to detect low-probability events such as HIV or to study the cumula
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Caspase-3/7 Inhibitor La entrega del n mero correspondiente
2019-06-13
La entrega del número 57, correspondiente al segundo semestre de 2013, ofrece la sección Mirador Latinoamericano, donde se abordan distintos aspectos de la cultura y la literatura en nuestra América. En primer lugar, en el artículo “Crítica literaria y opinión pública: polémicas literarias en Colomb
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A partir de las consideraciones que
2019-06-13
A partir de las consideraciones que distinguen la institucionalización formal e informal, O’Donnell hace un llamado PI103 tener en cuenta las especificidades de las democracias de América Latina y plantea que algunas democracias han subsistido, se han mantenido en el tiempo aun con la presencia de i
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A coleta de dados para pesquisa ocorreu com diversas
2019-06-13
A coleta de dados para pesquisa ocorreu com diversas técnicas. In-vestigações em endereços eletrônicos, jornais, revistas, livros, artigos. En trevistas pessoalmente, por telefone e emails. Os autores também mantiveram contato via correspondências com todas as organizações relacionadas no Quadro 1 e
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Fig shows an example of RNRVAS in a
2019-06-12
Fig. 3 shows an example of RNRVAS in a dual-chamber pacemaker recipient with sinus node disease, with the pacemaker set in rate adaptive DDI-R mode pacing with an AV interval of 300ms and lower rate limit of 60ppm. The tracing shows sensor-driven DDIR pacing at 80bpm (V–V pitavastatin length=750ms).
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The management of PEComa follows the same treatment principl
2019-06-12
The management of PEComa follows the same treatment principles as other subtypes of soft tissue sarcoma. Surgical resection remains the primary treatment modality. There is no consensus on the administration of adjuvant treatment. Other treatment options, including chemotherapy and radiotherapy, hav
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br Materials and methods br Results
2019-06-12
Materials and methods Results and discussion ABT-737 is a BH3-mimetic targeting Bcl-2, Bcl-XL and Bcl-W. The aim of the experiments was to test whether inhibition of Bcl-2 and Bcl-XL using ABT-737 can eradicate the CD34+/CD38− AML cell population. Bone marrow MNCs from patients (Table 1) were
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Where does this leave the other potential
2019-06-12
Where does this leave the other potential vaccines, and what additional information is required to inform their use? Many of these vaccines are based on a non-replicating adenoviral vector modified to express the Ebola glycoprotein (eg, adenovirus 5 (Ad5-ZEBOV), chimpanzee adenovirus 3 (Chad3), or a
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IRF expression had previously been described as a factor tha
2019-06-12
IRF1 expression had previously been described as a factor that contributes to susceptibility for HIV-1 infection [14]. Our findings evidenced a different expression modulation of this transcription factor in the two groups of DC according with the expression of the important Th1 driving cytokine IL-
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In patients with syncope episodes detecting type ECG
2019-06-12
In patients with syncope episodes, detecting type 1 ECG (spontaneous or drug-induced) and evaluating the characteristics of symptoms are important for determining the indication for ICD implantation. The result of EPS is supportive; however, it should be noted that VF is not induced during EPS in al
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Introduction Atrial fibrillation AF is a common cardiac arrh
2019-06-12
Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia that becomes more prevalent with age [1] and is associated with an increased long-term risk of stroke, motor protein failure, and all-cause mortality [2]. Since Einthoven recorded the electrograms in 1906 [3], AF has widely been
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Introduction Paraneoplastic immune mediated encephalopathy
2019-06-12
Introduction Paraneoplastic immune-mediated encephalopathy is a newly described disease. In 2005, Vitaliani et al first reported that four young women with ovarian teratoma (OT) had developed acute psychiatric and neurologic symptoms, e.g., seizures, memory deficits, decreased level of consciousnes
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A type saddle back type or type ST segment
2019-06-12
A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b
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