• The efficiency of additional strategies for eliminating the

  2019-05-23

  

  The efficiency of 2 additional strategies for eliminating the substrate for AF maintenance in addition to PVI has been described. Linear lesions are commonly made at the roof between the contralateral superior PVs (roof line), and at the isthmus between the mitral valve and the left inferior PV (mit

• Preference for injectable therapy over

  2019-05-23

  

  Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne

• Eosinophilia often occurs as a secondary

  2019-05-22

  

  Eosinophilia often occurs as a secondary process due to parasitic infections, allergy, GSK2194069 disease, malignancy, or drug reactions. When secondary causes of eosinophilia are excluded, one must consider HES, which is defined as a peripheral eosinophil count of greater than 1.5×109/L on at lea

• At follow up in the hematological

  2019-05-22

  

  At follow-up in the hematological out-patient clinic the patient had a normal HCT and the platelet count was slightly elevated at 515×109/L. However, no further cytoreductive treatment was initiated. At the beginning of 2011 (31 months after the PV-diagnosis) osteoporosis was diagnosed. Consequently

• br Methods br Results br Discussion br

  2019-05-22

  

  Methods Results Discussion Conclusions Conflict of interest Acknowledgments We thank Mr. John Martin for his linguistic assistance, and Mr. Jiro Suto for technical assistance in developing the QRS-T subtraction program. This study was supported by the Fukuda Foundation for Medical

• br Material and methods br Results br

  2019-05-22

  

  Material and methods Results Discussion In our series, fracture progression was noted in 53% of the lesions and 5 patients presented with new fractures after RT. Previous studies reported on the rate of pathologic fractures after single or multifraction RT; however, they did not stratify be

• br The Global Burden of Disease

  2019-05-22

  

  The Global Burden of Disease Study notes a substantial decrease in long-established global health threats such as communicable diseases and malnutrition, while underscoring the rise in non-communicable diseases and years lived with potentially disabling illnesses and injuries. One important but la

• The WHO Safer Primary Care report has grappled

  2019-05-22

  

  The WHO Safer Primary Care report has grappled head-on with the challenges associated with many variations in the scope, nature, and provision of primary care in different countries; insufficient data from low-income and middle-income country settings to inform priorities for care; the need to devel

• De esta poca son los primeros testimonios de

  2019-05-22

  

  De esta época son los primeros testimonios de la idea de fundar un periódico en París: en una carta del 7 de agosto de 1848, Eugène Carpentier, futuro administrador de La Tribune des Peuples, le presenta SB 203580 hydrochloride Mickiewicz un presupuesto estimado de lo que costaría un periódico. De c

• br Considera es finais Tentamos ainda

  2019-05-22

  

  Considerações finais Tentamos ainda incluir ao longo do texto o trabalho de campo que se realiza na comunidade quilombola de Capoeiras, no estado do Rio Grande do Norte. É de lá que absorvemos experiências que pudemos considerar vivenciais e que tutelam os sentidos das nossas buscas teóricas e ac

• IL IL is another potential inhibitor of OBL differentiation

  2019-05-22

  

  IL-7: IL-7 is another potential inhibitor of OBL differentiation in MM that induces RANKL production by T lymphocytes [113] and mediates MM-induced OBL inhibition by down-regulating RUNX2 transcriptional activity [93]. IL-7 levels are increased in the marrow of MM patients and that IL-7 inhibited bo

• A previous study from our group demonstrated that the

  2019-05-22

  

  A previous study from our group demonstrated that the truncated form of OPG (1-194) has greater activity than the complete form, given that proteoglycans present in the bone tumor microenvironment may bind to full length OPG, thereby limiting its bioavailability and bioactivity [31]. Therefore the t

• Based on these preliminary clinical results

  2019-05-22

  

  Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1

• br Discussion br Conclusions br Conflicts

  2019-05-22

  

  Discussion Conclusions Conflicts of interest Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotional stress or exercise in patients without organic heart disease and may be polymorphic or bidirectional (Fig. 1) [1–3]. This ventricular arrhythmia

• More recently Brugada et al used flecainide to identify the

  2019-05-22

  

  More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial

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