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br Role of the funding
2019-05-05
Role of the funding source Contributions Conflicts of interest Acknowledgments The authors would like to thank the patients who participated in this study and their families. The authors would also like to acknowledge the writing assistance of Stephen Mosley, Ph.D., of Knowledge Point 36
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The PAX gene encodes a transcriptional factor which is speci
2019-05-05
The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat
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HBV DNA levels are associated with clinically significant pa
2019-05-05
HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo
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sirtuin inhibitors Despite these recommendations diagnosing
2019-05-05
Despite these recommendations, diagnosing CIED infection could be challenging. Early after implantation procedure it is important to differentiate CIED pocket infection from incisional erythema or superficial wound infection or stitch abscess. These cases usually resolve with local measures and some
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Therefore other imaging techniques and
2019-05-05
Therefore, other imaging techniques and tools have been evaluated. The results of this study add to the body of evidence demonstrating the value of SPECT and the need for a multifactorial approach to patient selection for CRT and in evaluating potential predictors of CRT response in non-ischemic pat
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Adriamycin HCl The first variant in the non
2019-05-05
The first variant in the non-spine topic describes a patient with an excellent performance status, a favorable life expectancy, and an asymptomatic Adriamycin HCl lesion which does not pose an obvious risk for pathologic fracture. While the authors acknowledge that research has begun to determine w
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Many studies over the past years have
2019-05-05
Many studies over the past 20 years have shown the potential of urinary markers in the detection of the presence of bone metastases [3–11], the use of urinary markers for its prognostic value in bone disease [2,4,12–20], as well as directing therapy for bone metastases patients [2,6,12–18,21–25]. Th
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The strategy seeks to reduce
2019-05-05
The 25×25 strategy seeks to reduce preventable mortality. This emphasis leads to the selection of the four disorders specified in the strategy (cardiovascular disease, diabetes, cancer, and chronic respiratory disease), which account for 87% of all deaths from NCDs (). However, when the burden of di
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br Health research consortia in sub Saharan
2019-05-05
Health research consortia in sub-Saharan Africa present a positive outlook for the region through increased scientific capacity. New networks of African–African, African–European, and African–global partnerships provide platforms to advance crucial research domains. Such networks enable junior Afr
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br Discussion The presence of metastases at
2019-05-04
Discussion The presence of metastases at the time of diagnosis is a significant prognostic factor in osteosarcoma [14]. Skeletal metastases at time of presentations appears to carry a worse prognosis than pulmonary metastases [15]. Furthermore, the chance of survival can be improved by surgical r
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In contrast median Cu level mg L in our study
2019-05-04
In contrast, median Cu level (0.73 mg/L) in our study was approximately 50% lower than that in maternal blood (1.47 mg/L). Our result is consistent with several previously published studies, which showed a 50–60% decrease in Cu level in the fetus. The observed decrease in fetal Cu, a major metallic
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Introduction Paraneoplastic immune mediated encephalopathy i
2019-05-04
Introduction Paraneoplastic immune-mediated encephalopathy is a newly described disease. In 2005, Vitaliani et al first reported that four young women with ovarian teratoma (OT) had developed acute psychiatric and neurologic symptoms, e.g., seizures, memory deficits, decreased level of consciousnes
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Funding secured by Not applicable Data collection Sheldon M
2019-05-04
Funding secured by: Not applicable. Data collection: Sheldon M. Singh, MD, Ramanan Kumareswaran, MD. Conflict of interest Acknowledgments Introduction Early repolarization pattern (ERP) is characterized by an elevation greater than 0.1mV of the junction between the end of the QRS complex
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br Conclusions br Conflict of interest
2019-05-04
Conclusions Conflict of interest Introduction Radiofrequency (RF) catheter ablation is an established method of therapy for symptomatic supraventricular tachycardia (SVT). It has gained widespread acceptance for the treatment of accessory pathways in pediatric SVTs [1]. Accessory pathways a
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Mismo fen meno se observa
2019-05-04
Mismo fenómeno se observa en El Museo Mexicano, publicación ciertamente exitosa y donde se dieron cita los escritores más sobresalientes de la literatura mexicana decimonónica entre los años 1843 hasta 1846. El epígrafe que remata la portada constituye, en términos programáticos, todo una declaració
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