• The management of PEComa follows the same treatment principl

  2019-06-12

  

  The management of PEComa follows the same treatment principles as other subtypes of soft tissue sarcoma. Surgical resection remains the primary treatment modality. There is no consensus on the administration of adjuvant treatment. Other treatment options, including chemotherapy and radiotherapy, hav

• br Materials and methods br Results

  2019-06-12

  

  Materials and methods Results and discussion ABT-737 is a BH3-mimetic targeting Bcl-2, Bcl-XL and Bcl-W. The aim of the experiments was to test whether inhibition of Bcl-2 and Bcl-XL using ABT-737 can eradicate the CD34+/CD38− AML cell population. Bone marrow MNCs from patients (Table 1) were

• Where does this leave the other potential

  2019-06-12

  

  Where does this leave the other potential vaccines, and what additional information is required to inform their use? Many of these vaccines are based on a non-replicating adenoviral vector modified to express the Ebola glycoprotein (eg, adenovirus 5 (Ad5-ZEBOV), chimpanzee adenovirus 3 (Chad3), or a

• IRF expression had previously been described as a factor tha

  2019-06-12

  

  IRF1 expression had previously been described as a factor that contributes to susceptibility for HIV-1 infection [14]. Our findings evidenced a different expression modulation of this transcription factor in the two groups of DC according with the expression of the important Th1 driving cytokine IL-

• In patients with syncope episodes detecting type ECG

  2019-06-12

  

  In patients with syncope episodes, detecting type 1 ECG (spontaneous or drug-induced) and evaluating the characteristics of symptoms are important for determining the indication for ICD implantation. The result of EPS is supportive; however, it should be noted that VF is not induced during EPS in al

• Introduction Atrial fibrillation AF is a common cardiac arrh

  2019-06-12

  

  Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia that becomes more prevalent with age [1] and is associated with an increased long-term risk of stroke, motor protein failure, and all-cause mortality [2]. Since Einthoven recorded the electrograms in 1906 [3], AF has widely been

• Introduction Paraneoplastic immune mediated encephalopathy

  2019-06-12

  

  Introduction Paraneoplastic immune-mediated encephalopathy is a newly described disease. In 2005, Vitaliani et al first reported that four young women with ovarian teratoma (OT) had developed acute psychiatric and neurologic symptoms, e.g., seizures, memory deficits, decreased level of consciousnes

• A type saddle back type or type ST segment

  2019-06-12

  

  A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b

• Autophagy can be generally divided

  2019-06-12

  

  Autophagy can be generally divided into non-selective bulk autophagy and selective autophagy. Non-selective autophagy breaks down proteins and organelles to provide the cell with nutrients in response to starvation. Selective autophagy removes damaged and excess organelles as well as protein buy T09

• Universalisation means reaching all individuals with good qu

  2019-06-12

  

  Universalisation means reaching all individuals with good quality, effective interventions without financial hardship. Coverage matters. Participatory women\'s groups are effective in reducing newborn mortality among poor populations provided they involve about 30% of pregnant women in the populatio

• On the other hand it was also shown

  2019-06-11

  

  On the other hand, it was also shown that multi-fraction long-course radiotherapy results in better re-calcification and fewer recurrences of spinal cord salubrinal within the irradiated spinal region [24,25]. In case of recurrence, Nieder et al. [10] reviewed that re-irradiation of the spinal cord

• br Monitoring coagulation levels Coagulation levels can be

  2019-06-11

  

  Monitoring coagulation levels Coagulation levels can be monitored after warfarin treatment by measuring the prothrombin time (PT). However, monitoring is not needed for novel anticoagulants because these drugs have a much wider therapeutic range than warfarin. Nonetheless, in patients at high ris

• br Methods br Results br Discussion br Conclusion br Conflic

  2019-06-11

  

  Methods Results Discussion Conclusion Conflict of interest Introduction Placement of the left ventricular (LV) pacing lead in a tributary of the coronary sinus (CS) is one of the most challenging technical aspects of cardiac resynchronization therapy (CRT) device implantation. Fail

• br Methods br Discussion This study demonstrated

  2019-06-11

  

  Methods Discussion This study demonstrated that upgrading to CRT from RVAP improved cardiac performance and myocardial perfusion at pacing sites by SPECT. RVAP has been reported to alter left ventricular electrical and mechanical activation in a manner that is similar to the complete left bund

• br Methods br Results br Discussion A baumannii

  2019-06-11

  

  Methods Results Discussion A. baumannii remains one of the most common nosocomial pathogens and frequent causes of outbreaks in burn wound infections. Unfortunately, most of the isolates are resistant to antimicrobial agents. β-Lactamases are microbial enzymes that hydrolytically inactivate

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