• br Disclaimer br Conflicts of interest br

  2025-01-18

  

  Disclaimer Conflicts of interest Role of the Sponsor Acknowledgements Funding/support: This project was supported by a grant from the Department of Surgery (R5129), Western University and by the Institute for Clinical Evaluative Sciences (ICES) Western site. ICES is funded by an annual g

• br Concluding Remarks and Future Directions The physiologica

  2025-01-18

  

  Concluding Remarks and Future Directions The physiological significance of autophagy in neuronal function is steadily emerging. The studies discussed herein reveal that key neuronal functions, such as neurotransmitter release, pruning of dendritic spines, and behavioural outputs of neural network

• Phosphoinositide kinase PI K Akt

  2025-01-18

  

  Phosphoinositide 3-kinase (PI3K)/Akt has been well demonstrated in the protection of myocardial cell against IR injury via increasing cardiomyocyte survival, inhibiting excessive autophagy, et al. (Kong et al., 2016). The cetp inhibitors of ERK1/2 also involves in the regulation of cardiac myocyte

• ASK has been identified as an ASK binding protein Wang

  2025-01-18

  

  ASK2 has been identified as an ASK1 binding protein (Wang et al., 1998). ASK1 supports the stability and active configuration of ASK2 in the heteromeric complex, while ASK2 has been found to activate ASK1 by direct phosphorylation (Takeda et al., 2007). Unlike ASK1, which is ubiquitously expressed i

• The previous reports studied only the apoptosis process in

  2025-01-18

  

  The previous reports studied only the apoptosis process in a single cell. In our case we generalized these models inspired by the results of Albeck et al. (2008) and Raychaudhuri et al. (2008), to study the apoptosis cell death after photodynamic therapy in those areas of the tumor that are not expo

• br Results br Discussion br STAR Methods

  2025-01-18

  

  Results Discussion STAR★Methods Author Contributions Acknowledgments We thank Angela Walker for assistance with the manuscript; Junlin Liu, Xiangxiang Gu, Na Chen, Lu Xue, and the BV Core Facility of iHuman Institute for their support; scientists and colleagues at Amgen Inc., Zhulun W

• HMGA proteins have also been linked to localized changes in

  2025-01-18

  

  HMGA proteins have also been linked to localized changes in chromatin/nucleosome structure and alterations of cellular phenotype during induction of gene transcription in activated T lymphocytes. An adaptive immune response is initiated when naïve resting T lymphocytes encounter their corresponding

• br Angiogenesis as a critical event in diabetic

  2025-01-18

  

  Angiogenesis as a critical event in diabetic retinopathy Angiogenesis refers to the abnormal proliferation of blood vessels during various pathological conditions. It acquires the stature of being one of the most detrimental events responsible for the progression of diabetic retinopathy. Angiogen

• br The lipoxygenase pathway in vascular physiology

  2025-01-18

  

  The 12/15-lipoxygenase pathway in vascular physiology and pathology The mammalian 12- and 15-LOXs have high substrate specificity oxidizing predominantly ω−6 (arachidonic and linoleic acids) but also the ω−3 (docosahexanoic) UO 126 [86], [87], [88]. Different LOXs oxidize fatty acids both in the

• MT SGL encourages a individual feature

  2025-01-17

  

  MT-SGL encourages (a) individual feature selection based on the utility of the features across all tasks with ℓ2,1-norm and (b) task specific group selection based on the utility of the group with G2,1-norm, i.e., colorimetric regions of interest (ROI) for that task. Unlike basic SGL for regression

• DPP4 Activity Fluorometric Assay Kit mg br Acknowledgements

  2025-01-17

  

  Acknowledgements Introduction Diabetic complications are responsible for increased morbidity and mortality of diabetic patients. Increased flow of DPP4 Activity Fluorometric Assay Kit mg through the polyol pathway under conditions of hyperglycemia contributes to the development of diabetic co

• A highly attenuated B pertussis strain named BPZE has recent

  2025-01-17

  

  A highly attenuated B. pertussis strain, named BPZE1, has recently been described [10]. It produces enzymatically inactive pertussis toxin (PT), no dermonecrotic toxin and only trace amounts of tracheal cytotoxin. Markedly reduced lung pathology was observed in mice intranasally (i.n.) infected with

• Patients with ADA SCID may experience autoimmune

  2025-01-17

  

  Patients with ADA-SCID may experience autoimmune AEs after SCT (and/or during ERT) that are thought to be related to immune dysregulation prior to achieving complete immune reconstitution. The more common autoimmune manifestations include hemolytic anemia, hypothyroidism, and immune thrombocytopenia

• In addition we performed Western blot analysis of different

  2025-01-17

  

  In addition, we performed Western-blot analysis of different areas of mouse brain with melk pathway against mAck1 (Ureña et al., 2005). The data obtained showed a high rate of expression in neocortex, hippocampus, cerebellum, and brainstem (Fig. 4). More moderate levels of expression were seen in hy

• The first result of this

  2025-01-17

  

  The first result of this paper is parallel to the positivity result given in [16]: Here the definition of approximate ACHE metric is the same as in [18]. See Definition 1 for details. The second result of this paper is parallel to the Wnt agonist 1 extension formulae given in [2]. In particular, w

15280 records 21/1019 page Previous Next First page 上5页 2122232425 下5页 Last page