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The current results also demonstrated tendencies toward decr
2023-02-10
The current results also demonstrated tendencies toward decreased serum Aβ40 levels and increased Aβ42 levels during the 1-year follow-up. These tendencies are consistent with the results of a previous study that evaluated Aβs in the CSF of patients with late-life depression (Pomara et al., 2016). T
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br Introduction AMPA receptors AMPARs mediate the majority o
2023-02-10
Introduction AMPA receptors (AMPARs) mediate the majority of fast excitatory postsynaptic currents (EPSCs) in the Pyrimethamine australia (Jonas, 2000). The brevity of EPSCs and rapid deactivation of AMPARs depend upon a short lifetime of synaptically released glutamate, estimated to be about 1
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This study demonstrates numerical alterations of creatinine
2023-02-09
This study demonstrates numerical alterations of creatinine levels potentially reflecting ongoing or even higher myocardial contraction of the LAA after successful LAAC. Creatinine is the direct breakdown product of creatine in muscle, the key metabolite for energy supply during muscular and myocard
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This study demonstrates numerical alterations of creatinine
2023-02-09
This study demonstrates numerical alterations of creatinine levels potentially reflecting ongoing or even higher myocardial contraction of the LAA after successful LAAC. Creatinine is the direct breakdown product of creatine in muscle, the key metabolite for energy supply during muscular and myocard
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This study demonstrates numerical alterations of creatinine
2023-02-09
This study demonstrates numerical alterations of creatinine levels potentially reflecting ongoing or even higher myocardial contraction of the LAA after successful LAAC. Creatinine is the direct breakdown product of creatine in muscle, the key metabolite for energy supply during muscular and myocard
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The fat body is one
2023-02-09
The fat body is one of the largest tissues of Bombyx mori, with components including fat, glycogen, protein and vitamins. The fat body exhibits important physiological functions, not only storing a large number of nutrients but also serving as an important site of biosynthesis and metabolism (Arrese
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Prostate cancer is the second leading cause of cancer relate
2023-02-08
Prostate cancer is the second leading cause of cancer-related death in men in the United States [25]. Similar to pancreatic cancer, prostate cancer has few diagnostic options available, particularly to differentiate indolent from aggressive disease. Axl is also overexpressed in ∼50% of prostate canc
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br Results br Discussion br Conclusion The flux
2023-02-08
Results Discussion Conclusion The flux of glucose into cytosolic short chain acyl-CoAs was maintained in pure beta Chlorpropamide in the presence of inhibition of ATP citrate lyase with hydroxycitrate and also in a cell line with >90% ATP citrate lyase knockdown suggesting that a pathway o
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br Experimental and simulation section br Acknowledgments
2023-02-08
Experimental and simulation section Acknowledgments Financial support for this work was provided by the National Natural Science Foundation of China (No. 81101688). We would like to thank NC State University High Performance Computing Center for providing us computing resources, and Dr. Lihui
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br HMG proteins mobile modulators of chromatin structure
2023-02-08
HMG proteins: mobile modulators of chromatin structure and cellular phenotype The term “High Mobility Group” was originally coined for the HMG proteins because of their unusual solubility properties, their small size and their rapid mobility, relative to other chromatin proteins, during gel elect
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br Material and methods br Results br Discussion Aminopeptid
2023-02-08
Material and methods Results Discussion Aminopeptidase N is a transmembrane protease present in a wide variety of human tissues and cell types (endothelial, epithelial, fibroblast, leukocyte). APN expression is dysregulated in inflammatory diseases as well as in solid and hematologic tumors
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br Materials and methods br Results br Discussion In
2023-02-08
Materials and methods Results Discussion In the present study, we identified HBP1 as a novel substrate of AKT. This was demonstrated by in vitro phosphorylation assays and western blotting using phosphosite-specific antibodies. Three sites were identified by mass spectrometry and mutagenesi
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Introduction Dementia is a common
2023-02-07
Introduction Dementia is a common disease in the elderly, and a significant source of disability, healthcare spending, and long-term care admissions. There is evidence to suggest that testosterone plays a role in cognitive functioning, and lower serum levels correlate with higher amyloid deposits (
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A promising target that is involved in
2023-02-07
A promising target that is involved in the biosynthesis of the precursor LTA4 is the 5-LO-activating protein (FLAP), which in vivo is seemingly indispensable for LT formation [8], [9]. FLAP, a member of the MAPEG family (membrane-associated proteins in eicosanoid and glutathione metabolism), is an i
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br Discussion The measurement of gonadotropins FSH LH
2023-02-07
Discussion The measurement of Biperiden HCl (FSH, LH) is critical in the evaluation and assessment of 46,XX females presenting with primary amenorrhea and lack of pubertal development. A serum level of FSH higher than 40 U/L is diagnostic of ovarian failure (6), as seen in the present case. The
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