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Introduction Pneumocystis pneumonia PCP is
2022-07-05
Introduction Pneumocystis pneumonia (PCP) is a respiratory invasive infection caused by Pneumocystis jirovecii, an ubiquitous fungus. It is transmitted by air and mostly infects immunocompromised patients. PCP is characterized by respiratory complaints of cough, dyspnea, but also tachycardia, low g
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The conjugated gold is an
2022-07-05
The conjugated gold is an essential part of rapid test kits. For this PIs-IC strip the gold nanoparticles were conjugated with an optimal concentration of antibody to produce a stable nanoparticle solution (Fig. 3). From TEM images it became obvious that the colloid gold contained particles of diffe
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GSTP catalyzed reduction of Prdx enhances its peroxidase
2022-07-04
GSTP1-1 catalyzed reduction of Prdx6 enhances its peroxidase activity. Using standard NADPH/GR/GSH-coupled assays we used cell lysates from the transiently transfected Pranlukast to measure the influence of GSTP1 allelic variation on peroxidase activity. Specificity for detection of Prdx6 activity
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Both plant hormones and some
2022-07-04
Both plant hormones and some second messengers are involved in Fe-deficiency-related responses in plants (Kobayashi and Nishizawa, 2012). Among these second messengers, nitric oxide (NO) accumulation was induced by Fe deficiencies in tomato and Arabidopsis roots, and it acts as the downstream signal
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Introduction Glycogen synthase kinase GSK is an enzyme playi
2022-07-04
Introduction Glycogen synthase kinase-3 (GSK-3) is an enzyme playing multiple roles in animal tissues and organs, and Quinupristin-Dalfopristin Complex mesylate is not an exception. Apart from involvement in regulation of apoptosis and survival GSK-3 influences neuronal morphology, synapse formati
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The discovery that the physiological functions of LPI are
2022-07-04
The discovery that the physiological functions of LPI are associated with the activation of specific GPR55 membrane receptor [4] has launched a new era of research on this lysophospholipid. However, the activation of membrane receptors by lysophospholipids is extremely complex due to the multitude o
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In addition during the preparation of this
2022-07-04
In addition, during the preparation of this manuscript, Oka et al. [7] demonstrated that LPA acts as receptor ligand for GPR35 and that LPA is more potent than KYNA in eliciting a calcium mobilization (EC50: 30nM vs. 39μM for LPA and KYNA, respectively). Other endogenous GPR35 ligands, therefore, mi
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FDA-approved Drug Library br Regulation of gonadotropins by
2022-07-04
Regulation of gonadotropins by GnRH GnRH is released from the hypothalamus, and its release pattern is known to be pulsatile. That is, the pulse frequency and amplitude of GnRH release vary physiologically during reproductive cycles in females, and differentially stimulate the production and rele
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br Functional organization of postsynaptic glutamate recepto
2022-07-04
Functional organization of postsynaptic glutamate receptors Downstream effects of glutamate receptor positioning Mechanisms underlying the subsynaptic positioning of glutamate receptors Conclusions and future prospects The molecular organization of synapses is undoubtedly a critical dete
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Regarding the causative diseases of ES patients with
2022-07-04
Regarding the causative diseases of ES, patients with unknown cause and those with encephalitis had significantly higher CSF levels of CCT007093 against GluN2B-NT2 and GluN2B-CT than the disease controls, but patients with genetic disorder and those with cortical dysplasia showed no significant dif
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The plasma levels of glucose and amino acids at
2022-07-04
The plasma levels of glucose and amino acids at day 0 likely represent the function in utero since the blood was collected within 2h after birth. To elucidate the roles of intestinal transporters as determinants of plasma levels of glucose and amino acids, we analyzed the correlation between the exp
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2-Chlorotrityl Chloride Resin In order to test the influence
2022-07-04
In order to test the influence of the initial depolarization, experiments were performed, where the degree of chloride substitution was varied, either by adding n-Ringer to 2-Chlorotrityl Chloride Resin incubated in a sucrose Ringer or by suspending the cells directly in Ringers identical to the fi
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br Conflict of interest br Introduction Milk
2022-07-04
Conflict of interest Introduction Milk and dairy products are nutritious foods that provide lactose, calcium, phosphorous, magnesium and proteins, among other nutrients, which have been reported to have a fundamental role in bone development and healthy diets. An adequate consumption of dairy
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To obviate the mitogenic FGF activity
2022-07-04
To obviate the mitogenic FGF19 activity, several engineered FGF19 variants have been generated aiming to maintain the metabolic activity excluding the protumorigenic ones. One variant, M70, that differs from wild-type FGF19 by 5-amino acids deletion at the N-terminus and the substitution of 3-amino
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The canonical tumor suppressor p has also been
2022-07-02
The canonical tumor suppressor p53 has also been implicated as a transcriptional mediator of ferroptotic death (Jiang et al., 2015, Tarangelo et al., 2018, Wang et al., 2016, Xie et al., 2017). Specifically, p53 negatively regulates transcription of SLC7A11, the cystine-glutamate antiporter (Xc-) (J
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