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Although SCN A variants account for of
2019-04-29
Although SCN5A variants account for 18–28% of BrS [196], SCN5A genetic testing is complicated by an approximately 3–5% “benign” variant frequency in the general population [194]. Therefore, even in the most common genetic cause of BrS, 1 in 10 “positive” tests could be a “false- positive” even if fo
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Introduction Pulmonary vein isolation PVI is an established
2019-04-29
Introduction Pulmonary vein isolation (PVI) is an established strategy of paroxysmal atrial fibrillation (PAF) ablation [1–3]. Radiofrequency catheters have been the standard for AF ablation; however, PVI using balloon-based ablation has been increasingly adopted by electrophysiology laboratories a
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Un recurso semejante al empleado por Eloy
2019-04-29
Un recurso semejante al empleado por Eloy Martínez lo podemos encontrar en Agosto. Una vez que los implicados en el asesinato del edificio Deauville reconocen que Mattos se les acerca peligrosamente, deciden eliminar el único punto frágil de su coartada: el portero (Raimundo) del edificio, de quien
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Patient a year old man with RAEB and severe chronic
2019-04-29
Patient 2, a 54-year-old man with RAEB 2, and severe chronic obstructive pulmonary disease, struggled through induction chemotherapy with daunorubicin plus cytarabine (DA) 3+10. Second DA 3+8 produced delayed hematopoietic recovery. CR1 was documented after course 1 and lasted 18 months. Relapse was
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br Conflict of interests br Chronic lymphocytic leukemia CLL
2019-04-29
Conflict of interests Chronic lymphocytic leukemia (CLL) is the most frequent hematologic neoplasm in Western countries. The clinical course of chronic lymphocytic leukemia ranges from a very indolent disorder with a normal lifespan, to a rapidly progressive disease leading to death. The variab
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br Conflict of interest br Authorship contributions br
2019-04-29
Conflict of interest Authorship contributions Introduction Clofarabine, a purine nucleoside analog of cladribine, is used in adult and pediatric regimens to treat Acute Myeloid Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL). Use of clofarabine has been studied as monotherapy [1] and
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br Materials and methods br Results br Discussion Interest i
2019-04-28
Materials and methods Results Discussion Interest in phenolic compounds has grown over the last several decades owing to the recognition of their antioxidant properties and their probable role in the prevention of a number of pathologies associated with oxidative stress [23]. Taking into ac
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br Escribir y destacar promoci n
2019-04-28
Escribir y destacar (promoción 1975-1985): la identidad por las diferencias ¿Cómo escribir dentro de un mercado de tantos competidores para un país de escasos lectores? En México, ni siquiera los estudiantes de la universidad consumen libros y hay más papelerías que librerías (Zaid 2013: 143-154
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Con todo esto en mente nos acercamos a revisar
2019-04-28
Con todo esto en mente nos acercamos prostanoid revisar uno de los volúmenes de la colección: La literatura hispanoamericana, escrito por Rafael Olea Franco, Julio Ortega y Liliana Weinberg. II La literatura latinoamericana se presenta, de esta manera, como respuesta positiva y complejizante de
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CD is a type I
2019-04-28
CD147 is a type I transmembrane glycoprotein of the immunoglobulin superfamily. CD147 has been reported to regulate the expression of P-gp and affect apoptosis in cancer buy BGJ398 with MDR phenotype [10,13,14]. In the present study, drug-free K562/ADR was first established by culturing K562/ADR in
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In Syria since the start of the conflict in there
2019-04-28
In Syria, since the start of the conflict in 2011, there have been 223 attacks on 175 health facilities; these attacks have killed 599 medical personnel. In 2015 alone, more than 90 airstrikes and shelling attacks hit facilities supported by MSF in Syria. Despite the global attention directed toward
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The measurement of the PPI of
2019-04-28
The measurement of the PPI of DP following entrainment pacing usually consists of measuring the interval between the last capturing stimulus and the next DP. This technique is generally based on the assumption that, in the presence of 1:1 capture, pacing depolarizes the zone of slow conduction in t
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In this section we will try
2019-04-28
In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma
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Residing in West Germany also decreased BIS persistence In J
2019-04-28
Residing in West Germany also decreased BIS persistence. In 2015, Jacob et al. demonstrated in 4,915 BC women that the treatment discontinuation rate is higher in West Germany than in East Germany [1]. Finally, our study returned one outcome that requires careful discussion: we found that private he
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Finally the effects of In NLS CSL on hematopoietic
2019-04-28
Finally, the effects of 111In-NLS-CSL360 on hematopoietic function in healthy Balb/c mice was studied. Groups of 2–4 mice were injected i.v. with 6.1±1.4MBq, 18.8±1.5MBq or 35.8±0.9MBq of 111In-NLS-CSL360 or an equivalent mass (70μg) of unlabeled CSL360 or received normal saline. At two weeks post-t
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